# Staff Scientist at BCC-NIH

Staff Scientist at BCC-NIH in Bethesda MD. Remote, paying $110k–$140k. Posted March 30, 2026.

- Company: BCC-NIH
- Location: Bethesda MD
- Workplace: Remote
- Pay: $110k–$140k
- Experience: 5+ years
- Posted: 2026-03-30
- Apply: https://job-boards.greenhouse.io/bcc/jobs/7684124003
- Source: https://jobmagic.ai/jobs/staff-scientist-bcc-nih-qe38x2

## Requirements

- PhD in Computer Science, Computational Biology, Bioinformatics, or a related field
- Minimum of 5 years of experience developing and deploying machine learning or deep learning models
- Strong experience with cloud platforms (AWS, GCP, or Azure)
- Proficiency in deep learning frameworks (PyTorch preferred; TensorFlow or HuggingFace acceptable)
- Deep understanding of neural network architectures (CNNs, transformers, sequence models)
- Strong programming skills in Python and experience working in Linux-based environments
- Experience with MLOps practices, including experiment tracking and model versioning
- Experience building and deploying containerized workflows (Docker and/or Singularity)
- Experience with distributed training across GPUs or multi-node environments
- Strong knowledge of genomics, gene regulation, and epigenomics
- Experience working with large-scale biological datasets (e.g., ENCODE, Roadmap Epigenomics, UCSC Genome Browser)
- Familiarity with genomics data formats (FASTA, VCF, BAM/CRAM, BED)

## Description

### Overview

Black Canyon Consulting is seeking a **Staff Scientist** to work with a Principal Investigatory in the National Institutes of Health at the National Library of Medicine to support the development of high-fidelity artificial intelligence models designed to decode the functional landscape of the human and mouse genomes. This effort will leverage Telomere-to-Telomere (T2T) reference assemblies to advance understanding of gene regulation, particularly within complex and repetitive genomic regions.

This position requires a unique combination of computational genomics expertise, machine learning proficiency, and scalable software engineering capabilities to support large-scale data integration and model development.

### **Responsibilities**

- Lead the design, development, and implementation of AI-driven models for gene regulation analysis

- Architect and scale a TREDNet-based framework for cloud-native execution

- Optimize models for distributed, multi-GPU training environments

- Integrate and analyze large-scale genomic and epigenomic datasets, including:

- ENCODE / modENCODE

- NIH Roadmap Epigenomics

- UCSC Genome Database

- Apply AI methodologies to functionally annotate repetitive genomic regions, including centromeres and telomeres

- Develop and maintain scalable, containerized pipelines using Docker and/or Singularity

- Implement MLOps best practices, including experiment tracking, model versioning, and reproducibility

- Deploy and manage workflows in cloud environments (AWS, GCP, or Azure)

- Collaborate with interdisciplinary teams across computational and life sciences domains

### **Required Qualifications**

- PhD in Computer Science, Computational Biology, Bioinformatics, or a related field

- Minimum of 5 years of experience developing and deploying machine learning or deep learning models

- Strong experience with cloud platforms (AWS, GCP, or Azure)

- Proficiency in deep learning frameworks (PyTorch preferred; TensorFlow or HuggingFace acceptable)

- Deep understanding of neural network architectures (CNNs, transformers, sequence models)

- Strong programming skills in Python and experience working in Linux-based environments

- Experience with MLOps practices, including experiment tracking and model versioning

- Experience building and deploying containerized workflows (Docker and/or Singularity)

- Experience with distributed training across GPUs or multi-node environments

- Strong knowledge of genomics, gene regulation, and epigenomics

- Experience working with large-scale biological datasets (e.g., ENCODE, Roadmap Epigenomics, UCSC Genome Browser)

- Familiarity with genomics data formats (FASTA, VCF, BAM/CRAM, BED)

### **Preferred Qualifications**

- Experience with Telomere-to-Telomere (T2T) genome assemblies

- Experience analyzing repetitive genomic regions (e.g., centromeres, telomeres)

- Background in regulatory, functional, or comparative genomics (e.g., human vs. mouse)

- Experience with hyperparameter tuning and large-scale model optimization

- Familiarity with genomic foundation models or sequence-based deep learning approaches

- Experience running ML workloads on GPU-enabled cloud or HPC environments

- Familiarity with workflow orchestration tools (e.g., Nextflow, Snakemake, Airflow)

- Experience transitioning research models into production-grade pipelines

- Familiarity with CI/CD and infrastructure-as-code tools (e.g., Terraform)

- Experience working in interdisciplinary teams

### **Deliverables**

- Develop a containerized (Docker/Singularity) TREDNet pipeline capable of scaling across multiple GPU nodes in a cloud environment

- Produce a comprehensive functional map of the T2T reference genome, identifying regulatory motifs in previously unresolved regions

- Develop comparative models between human and mouse cell lines to identify conserved regulatory mechanisms

### **Benefits and Salary**

We attract the best people in the business with our competitive benefits package, including medical, dental, and vision coverage; a 401(k) plan with employer contribution; paid holidays, vacation, and tuition reimbursement.

We offer a competitive salary commensurate with experience and location. The targeted range for this position is $110,000 - $140,000.

If you enjoy being part of a high-performing, professional, technology-focused organization, please apply today!
